Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2023893 | 0.89 | MEN1 (0.73) | MEN1KMT2ATAAR1SLC6A4SLC6A3 | |
| SCHEMBL11197895 | 0.81 | TAAR1 (0.53) | TAAR1SLC6A4SLC6A3DRD2MIF | |
| SCHEMBL6817957 | 0.78 | MEN1 (0.62) | MEN1KMT2ATAAR1SLC6A4MPO | |
| SCHEMBL5110312 | 0.78 | MEN1 (0.57) | MEN1KMT2ATAAR1IDO1 | |
| SCHEMBL2573264 | 0.78 | MEN1 (0.57) | MEN1KMT2ATAAR1IDO1AGXT | |
| SCHEMBL27519748 | 0.78 | MEN1 (0.57) | MEN1KMT2ATAAR1DRD2MIF | |
| SCHEMBL3026516 | 0.78 | TAAR1 (0.53) | TAAR1SLC6A4SLC6A3DRD2IDO1 | |
| SCHEMBL9212090 | 0.77 | TAAR1 (0.57) | MEN1KMT2ATAAR1SLC6A4SLC6A3 | |
| SCHEMBL30645106 | 0.77 | TAAR1 (0.57) | MEN1KMT2ATAAR1SLC6A4SLC6A3 | |
| SCHEMBL3371633 | 0.77 | TAAR1 (0.74) | TAAR1SLC6A4SLC6A3DRD2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042275-A1 | ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES | NPS PHARMACEUTICALS, INC. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999029657-A1 | ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES | NPS PHARMACEUTICALS, INC. (US) | 1999-06-17 | — | — | WO | disclosed |