SCHEMBL11197899

SCHEMBL11197899

N=C(N)c1ccccc1NC(N)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.55
GAA P10253 3/20 0.55
POLB P06746 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 4/20 0.46
HPGD P15428 1/20 0.46
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
MAPT P10636 2/20 0.44
F10 P00742 2/20 0.44
KMT2A Q03164 2/20 0.44
F2 P00734 1/20 0.44
PLG P00747 1/20 0.44
PLAU P00749 1/20 0.44
PLAT P00750 1/20 0.44
CTSK P43235 1/20 0.44
LMNA P02545 1/20 0.44
CYP2C19 P33261 1/20 0.43
GFER P55789 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23249603 0.88 KDM4E (0.47) KDM4EGAAPOLBSMN1; SMN2ALDH1A1
SCHEMBL27493862 0.86 CYP2C19 (0.61) KDM4EPOLBSMN1; SMN2ALDH1A1HPGD
SCHEMBL10816174 0.85 KDM4E (0.42) KDM4EGAAPOLBSMN1; SMN2ALDH1A1
SCHEMBL28515351 0.85 KDM4E (0.53) KDM4EGAAPOLBSMN1; SMN2ALDH1A1
SCHEMBL9302237 0.83 F10 (0.49) KDM4EGAAPOLBSMN1; SMN2ALDH1A1
SCHEMBL5365142 0.83 KDM4E (0.65) KDM4EGAAPOLBSMN1; SMN2ALDH1A1
SCHEMBL2863439 0.82 KDM4E (0.50) KDM4EPOLBSMN1; SMN2ALDH1A1HPGD
SCHEMBL29840068 0.82 GAA (0.67) KDM4EGAAPOLBSMN1; SMN2ALDH1A1
SCHEMBL3928666 0.82 GAA (0.67) KDM4EGAAPOLBSMN1; SMN2ALDH1A1
SCHEMBL6326283 0.81 KMT2A (0.62) KDM4EPOLBALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0073276-A1 A method of increasing the feed efficiency of animals, and compositions for use in such a method RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-03-09 EP disclosed