Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10816174 | 0.89 | KDM4E (0.42) | F10GAALMNAPDCD1CD274 | |
| SCHEMBL9303445 | 0.88 | NPC1 (0.54) | F10NPC1GAATP53RAB9A | |
| SCHEMBL9302810 | 0.87 | NPC1 (0.49) | F10NPC1GAATP53RAB9A | |
| SCHEMBL9303221 | 0.87 | NPC1 (0.46) | F10NPC1TP53RAB9AHPGD | |
| SCHEMBL9303104 | 0.87 | NPC1 (0.49) | F10NPC1GAATP53RAB9A | |
| SCHEMBL11197899 | 0.83 | KDM4E (0.55) | F10GAALMNAPDCD1CD274 | |
| SCHEMBL9303615 | 0.83 | PDCD1 (0.55) | F10PDCD1CD274HPGDF2 | |
| SCHEMBL9304086 | 0.83 | PLAU (0.69) | F10F2PLGPLAUPLAT | |
| SCHEMBL30139987 | 0.82 | KDM4E (0.60) | NPC1LMNATP53RAB9APDCD1 | |
| SCHEMBL45762 | 0.82 | KDM4E (0.60) | NPC1LMNATP53RAB9APDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |