Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | HMGCR | P04035 | 2/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11171407 | 0.82 | HMGCR (0.48) | LPAR3LPAR2LPAR1HMGCRLMNA | |
| SCHEMBL5078168 | 0.82 | HMGCR (0.48) | LPAR3LPAR2LPAR1HMGCRLMNA | |
| SCHEMBL11154052 | 0.82 | HMGCR (0.48) | LPAR3LPAR2LPAR1HMGCRLMNA | |
| SCHEMBL5417159 | 0.82 | HMGCR (0.48) | LPAR3LPAR2LPAR1HMGCRLMNA | |
| SCHEMBL5410693 | 0.82 | HMGCR (0.48) | LPAR3LPAR2LPAR1HMGCRLMNA | |
| SCHEMBL5415808 | 0.82 | HMGCR (0.48) | LPAR3LPAR2LPAR1HMGCRLMNA | |
| SCHEMBL39022 | 0.82 | HMGCR (0.48) | LPAR3LPAR2LPAR1HMGCRLMNA | |
| SCHEMBL21814199 | 0.82 | HMGCR (0.48) | LPAR3LPAR2LPAR1HMGCRLMNA | |
| SCHEMBL21359725 | 0.82 | HMGCR (0.48) | LPAR3LPAR2LPAR1HMGCRLMNA | |
| SCHEMBL10984731 | 0.80 | HMGCR (0.49) | LPAR3LPAR2LPAR1HMGCRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421897-A | ADHESIVES, COATINGS, MOLDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1983-12-20 | — | — | US | disclosed |
| US-4339571-A | DIGLYCIDYL ISOPHTHALATE, OR TEREPHTHALATE | CIBA-GEIGY CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| US-4296231-A | CONTAINING A HYDROXY AND ETHER-CONTAINING AMINE COMPOUND AS A CURING CATALYST | CIBA-GEIGY CORPORATION (US) | 1981-10-20 | — | — | US | disclosed |