Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855413 | 0.93 | HRH3 (0.36) | HRH3HRH2HRH1MAOB | |
| SCHEMBL10505725 | 0.91 | HRH3 (0.40) | HRH3HRH2HRH1MAOB | |
| SCHEMBL2210788 | 0.91 | HRH3 (0.40) | HRH3HRH2HRH1MAOB | |
| SCHEMBL10505714 | 0.91 | HRH3 (0.40) | HRH3HRH2HRH1MAOB | |
| SCHEMBL2110831 | 0.91 | HRH3 (0.40) | HRH3HRH2HRH1MAOB | |
| SCHEMBL2948327 | 0.84 | ALOX15 (0.35) | HRH3HRH2HRH1NCF1 | |
| SCHEMBL6733745 | 0.84 | HRH3 (0.39) | HRH3HRH2HRH1MAOB | |
| SCHEMBL6733747 | 0.84 | HRH3 (0.39) | HRH3HRH2HRH1MAOB | |
| SCHEMBL23828681 | 0.84 | HRH3 (0.41) | HRH3HRH2HRH1MAOB | |
| SCHEMBL23828667 | 0.84 | HRH3 (0.41) | HRH3HRH2HRH1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068806-A2 | Basic acyl amides of (5-amino-1,3-dialkylpyrazol-4-yl)(aryl)methanones, processes for their production, and pharmaceutical compositions containing such compounds | WARNER-LAMBERT COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |