⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12137975 | 0.69 | — | — | |
| SCHEMBL19236339 | 0.67 | — | — | |
| SCHEMBL14676021 | 0.67 | — | — | |
| SCHEMBL2403456 | 0.67 | — | — | |
| SCHEMBL19236643 | 0.65 | — | — | |
| SCHEMBL12300185 | 0.65 | — | — | |
| SCHEMBL18558797 | 0.63 | — | — | |
| SCHEMBL642626 | 0.62 | — | — | |
| SCHEMBL6573739 | 0.62 | — | — | |
| SCHEMBL11415549 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109305989-B | Phosphamide derivative and preparation method and application thereof | 四川海思科制药有限公司 | 2021-02-26 | — | — | CN | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| EP-0075895-A2 | Pharmaceutical amides, and preparation, formulations and use thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-04-06 | — | — | EP | disclosed |