Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.37 |
| ▸ | MYLK | Q15746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200338 | 0.78 | TYR (0.49) | MEN1MAPTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL17559171 | 0.78 | MAPT (0.39) | IGF1RSRCAXLPTK2AURKB | |
| SCHEMBL29366917 | 0.76 | PRKCE (0.42) | IGF1RSRCAXLPTK2AURKB | |
| SCHEMBL14188453 | 0.76 | HTR1D (0.42) | IGF1RSRCAXLPTK2AURKB | |
| SCHEMBL11210633 | 0.76 | SRC (0.37) | IGF1RSRCAXLPTK2AURKB | |
| SCHEMBL5201009 | 0.75 | TSHR (0.33) | MEN1MAPTKMT2ACYP1A2TSHR | |
| SCHEMBL16335022 | 0.75 | ERN1 (0.35) | MEN1MAPTKMT2ACYP1A2TSHR | |
| SCHEMBL11201117 | 0.72 | MEN1 (0.39) | IGF1RSRCAXLPTK2AURKB | |
| SCHEMBL3631682 | 0.71 | ERN1 (0.46) | MEN1MAPTKMT2AALDH1A1RECQL | |
| SCHEMBL17371035 | 0.71 | PRKCE (0.40) | IGF1RSRCAXLPTK2AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080419-A2 | 8-Haloalkyl-4H-(1)-benzopyran-4-ones and preparation processes | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1983-06-01 | — | — | EP | disclosed |