Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.43 |
| ▸ | FAP | Q12884 | 2/20 | 0.43 |
| ▸ | RBP4 | P02753 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 3/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193895 | 0.82 | USP30 (0.43) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL11201841 | 0.81 | PREP (0.37) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL11202033 | 0.80 | BCHE (0.45) | DPP4FAP | |
| SCHEMBL11200439 | 0.80 | BCHE (0.45) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL11195633 | 0.80 | PREP (0.36) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL11193373 | 0.80 | BCHE (0.45) | DPP4DPP8DPP9FAPFFAR1 | |
| SCHEMBL11200386 | 0.77 | PREP (0.53) | DPP4FAP | |
| SCHEMBL11196337 | 0.77 | KIF11 (0.44) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL11200651 | 0.76 | MAPT (0.42) | — | |
| SCHEMBL4729725 | 0.76 | SMN1; SMN2 (0.50) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376731-A | 2-NITRILES THEREOF | BOEHRINGER MANNHEIM GMBH (DE) | 1983-03-15 | — | — | US | disclosed |