Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030787 | 0.83 | ALDH1A1 (0.50) | ALDH1A1RAB9APOLBKDM4ECYP1A2 | |
| SCHEMBL3024207 | 0.81 | PIM1 (0.41) | PIM1PIM3ALDH1A1ERN1RAB9A | |
| SCHEMBL11287001 | 0.77 | NR4A2 (0.41) | NPSR1ALDH1A1POLBNR4A2MAPT | |
| SCHEMBL4046793 | 0.76 | NR4A2 (0.47) | NR4A2 | |
| SCHEMBL26113851 | 0.74 | NPSR1 (0.37) | NPSR1ALDH1A1POLBNR4A2KDM4E | |
| SCHEMBL21561526 | 0.74 | TDP1 (0.38) | NPSR1RAB9APOLBNR4A2MAPT | |
| SCHEMBL3627973 | 0.74 | ALDH1A1 (0.40) | NPSR1ALDH1A1NR4A2MAPTKDM4E | |
| SCHEMBL6022276 | 0.73 | NR4A2 (0.41) | NR4A2 | |
| SCHEMBL11201376 | 0.73 | NPSR1 (0.43) | NPSR1NR4A2 | |
| Hydrochloric Acid SCHEMBL3113133 | 0.73 | ALDH1A1 (0.39) | NPSR1ALDH1A1NR4A2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068460-A1 | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO. INC. (US) | 1983-01-05 | — | — | EP | disclosed |