Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 20/20 | 0.80 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.80 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.80 |
| ▸ | PTGIS | Q16647 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pirmagrel SCHEMBL636018 | 0.89 | TBXAS1 (1.00) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10975502 | 0.89 | TBXAS1 (1.00) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10973204 | 0.89 | TBXAS1 (1.00) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10974315 | 0.89 | TBXAS1 (1.00) | TBXAS1PTGS1PTGS2PTGIS | |
| Pirmagrel SCHEMBL11069774 | 0.88 | TBXAS1 (0.97) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10980923 | 0.87 | TBXAS1 (1.00) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10646885 | 0.87 | TBXAS1 (0.78) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10974343 | 0.86 | TBXAS1 (0.81) | TBXAS1PTGS1PTGS2PTGIS | |
| Hydrochloric Acid SCHEMBL10978209 | 0.86 | TBXAS1 (1.00) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10648637 | 0.85 | TBXAS1 (1.00) | TBXAS1PTGS1PTGS2PTGIS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068386-A1 | Substituted imidazo(1,5-a)pyridines, process for their preparation and pharmaceutical preparations containing these compounds | CIBA-GEIGY AG (CH) | 1983-01-05 | — | — | EP | disclosed |