Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TK2 | O00142 | 6/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087407 | 0.82 | TK1 (0.53) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3079659 | 0.80 | TK1 (0.66) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3079661 | 0.80 | TK1 (0.66) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL11118415 | 0.79 | TK1 (0.56) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL11118409 | 0.79 | TK1 (0.56) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3089586 | 0.79 | TK1 (0.61) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3085003 | 0.79 | TK1 (0.61) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3084999 | 0.79 | TK1 (0.61) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3089583 | 0.79 | TK1 (0.61) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3078242 | 0.79 | TK1 (0.74) | TK1CYP1A2CYP3A4TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095294-A1 | Deoxyuridine compounds, methods for preparing them and their use in medicine | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |
| EP-0082668-A1 | 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections | BEECHAM GROUP PLC (GB) | 1983-06-29 | — | — | EP | disclosed |