Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30532583 | 0.86 | HTT (0.71) | HTTMEN1KMT2ANOTUMPDE4A | |
| SCHEMBL28647270 | 0.84 | HTT (0.69) | HTTKMT2ANOTUMPDE4APDE4B | |
| SCHEMBL9433063 | 0.83 | HTT (0.67) | HTTMEN1GAAKMT2ANOTUM | |
| SCHEMBL22086338 | 0.81 | HTT (0.47) | HTTBCAT2MEN1GAAKMT2A | |
| SCHEMBL20898163 | 0.81 | HTT (0.47) | HTTBCAT2MEN1GAAKMT2A | |
| SCHEMBL9805097 | 0.80 | HTT (1.00) | HTTMEN1GAAKMT2AEGFR | |
| SCHEMBL6469331 | 0.80 | HTT (0.44) | HTTCCNCCDK8PARP1IRAK4 | |
| SCHEMBL11163629 | 0.78 | HTT (0.64) | HTTMEN1GAAKMT2APIM1 | |
| SCHEMBL9805088 | 0.78 | HTT (0.73) | HTTMEN1GAAKMT2AMAPK1 | |
| Thiodiglycol SCHEMBL11184927 | 0.75 | HTT (0.57) | HTTKMT2ANOTUMPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369276-A | Pyrrole stabilizers for chlorine-containing thermoplastics | CIBA-GEIGY CORPORATION (US) | 1983-01-18 | — | — | US | disclosed |