Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.46 |
| ▸ | SGK1 | O00141 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29071906 | 0.87 | HTT (0.77) | HTTLMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9805088 | 0.84 | HTT (0.73) | HTTLMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL29071892 | 0.84 | HTT (0.73) | HTTLMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30532583 | 0.83 | HTT (0.71) | HTTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28647270 | 0.81 | HTT (0.69) | HTTLMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL11169340 | 0.81 | HTT (0.68) | HTTLMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6464873 | 0.81 | HTT (0.68) | HTTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9433063 | 0.80 | HTT (0.67) | HTTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11200539 | 0.80 | HTT (0.67) | HTTALDH1A1SMN1; SMN2MEN1KMT2A | |
| Pyrrole SCHEMBL9864136 | 0.80 | HTT (0.66) | HTTLMNAALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049602-A | Heat resistance | HUELS AKTIENGESELLSCHAFT (DE) | 1991-09-17 | — | — | US | disclosed |
| EP-0419794-A1 | Costabilizers for vinyl chloride polymerisate based mouldings | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | disclosed |
| EP-0419792-A1 | Pyrroles as costabilizers for vinylchloride polymerisate based mouldings | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | disclosed |