Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202267 | 0.85 | KDM4E (0.39) | ABCB1ALDH1A1MAPTKDM4EAPAF1 | |
| SCHEMBL11203967 | 0.84 | KDM4E (0.38) | ABCB1ALDH1A1MAPTKDM4EAPAF1 | |
| SCHEMBL11203366 | 0.82 | KHK (0.41) | ALDH1A1MAPTKDM4EPOLBHRH1 | |
| SCHEMBL11201393 | 0.81 | HRH1 (0.41) | ALDH1A1MAPTKDM4EAPAF1POLB | |
| SCHEMBL11197431 | 0.80 | HRH1 (0.40) | ALDH1A1MAPTKDM4EAPAF1POLB | |
| SCHEMBL11204593 | 0.80 | ABCB1 (0.43) | ABCB1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL5309322 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBHPGDLMNA | |
| SCHEMBL11197598 | 0.76 | PRKCI (0.47) | ALDH1A1MAPTKDM4EAPAF1POLB | |
| SCHEMBL11200211 | 0.76 | KDM4E (0.38) | ALDH1A1MAPTKDM4EAPAF1POLB | |
| SCHEMBL11202911 | 0.74 | HTR2C (0.55) | ABCB1ALDH1A1KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |