Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KHK | P50053 | 7/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204549 | 0.86 | KHK (0.46) | KHKPRKCIKMT5AHTR2CESR1 | |
| SCHEMBL11198016 | 0.86 | PRKCI (0.43) | KHKPRKCIHTR2CESR1 | |
| SCHEMBL11201921 | 0.85 | KHK (0.40) | KHKPRKCIKMT5AHTR2CESR1 | |
| Hydrochloric Acid SCHEMBL11207765 | 0.85 | KHK (0.46) | KHKPRKCIKMT5AHTR2CESR1 | |
| SCHEMBL11207434 | 0.85 | KDM4E (0.38) | KDM4EMAPTMAPK1ATMRAD52 | |
| SCHEMBL11197538 | 0.85 | PRKCI (0.41) | KDM4EMAPTKHKPRKCIHTR2C | |
| SCHEMBL11201871 | 0.85 | PRKCI (0.41) | KHKPRKCIHTR2CESR1 | |
| Hydrochloric Acid SCHEMBL11204595 | 0.85 | PRKCI (0.43) | KHKPRKCIHTR2CESR1 | |
| SCHEMBL11200114 | 0.80 | PRKCI (0.46) | KDM4EKHKPRKCIHTR2C | |
| Hydrochloric Acid SCHEMBL11197387 | 0.79 | PRKCI (0.45) | KDM4EKHKPRKCIHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |