Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 5/20 | 0.41 |
| ▸ | KHK | P50053 | 8/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197538 | 0.89 | PRKCI (0.41) | PRKCIKHKHTR2CESR1 | |
| SCHEMBL11204549 | 0.88 | KHK (0.46) | PRKCIKHKSTK17AHTR2CESR1 | |
| SCHEMBL11198016 | 0.87 | PRKCI (0.43) | PRKCIKHKHTR2CESR1CTSB | |
| Hydrochloric Acid SCHEMBL11207765 | 0.87 | KHK (0.46) | PRKCIKHKSTK17AHTR2CESR1 | |
| SCHEMBL11201921 | 0.87 | KHK (0.40) | PRKCIKHKSTK17AHTR2CESR1 | |
| Hydrochloric Acid SCHEMBL11204595 | 0.86 | PRKCI (0.43) | PRKCIKHKHTR2CESR1CTSB | |
| SCHEMBL11200699 | 0.85 | KDM4E (0.40) | PRKCIKHKHTR2CESR1 | |
| SCHEMBL11217766 | 0.84 | HCRTR1 (0.37) | PRKCIESR1 | |
| SCHEMBL11200114 | 0.83 | PRKCI (0.46) | PRKCIKHKHTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL11197387 | 0.82 | PRKCI (0.45) | PRKCIKHKHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |