Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202192 | 0.82 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 | |
| Doxpicomine SCHEMBL29356901 | 0.81 | SLC6A2 (0.38) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 | |
| Doxpicomine SCHEMBL11176546 | 0.81 | SLC6A2 (0.38) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL11203978 | 0.81 | LMNA (0.37) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 | |
| Doxpicomine SCHEMBL11865226 | 0.80 | TSHR (0.37) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 | |
| Doxpicomine SCHEMBL29658207 | 0.80 | TSHR (0.37) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 | |
| Doxpicomine SCHEMBL122961 | 0.80 | TSHR (0.37) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL11204457 | 0.80 | KCNA5 (0.36) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL11200368 | 0.78 | SMN1; SMN2 (0.35) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL11202272 | 0.78 | KCNA5 (0.34) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080847-A2 | Improvements in or relating to the synthesis of dioxane analgesics | ELI LILLY AND COMPANY (US) | 1983-06-08 | — | — | EP | disclosed |