Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.69 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.69 |
| ▸ | PGR | P06401 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269908 | 0.91 | SLC6A4 (0.78) | SLC6A4PDE3BPDE3ANR3C1PGR | |
| SCHEMBL9412170 | 0.89 | KCNH2 (0.69) | SLC6A4PDE3BPDE3ANR3C1PGR | |
| SCHEMBL11202877 | 0.89 | SLC6A4 (0.69) | SLC6A4PDE3BPDE3ANR3C1PGR | |
| SCHEMBL11200206 | 0.88 | PDE3B (0.69) | SLC6A4PDE3BPDE3ANR3C1PGR | |
| SCHEMBL7267767 | 0.86 | SLC6A4 (0.72) | SLC6A4PDE3BPDE3ANR3C1PGR | |
| SCHEMBL11202820 | 0.86 | NR3C1 (0.78) | SLC6A4PDE3BPDE3ANR3C1PGR | |
| SCHEMBL9128429 | 0.86 | SLC6A4 (0.68) | SLC6A4PDE3BPDE3ANR3C1PGR | |
| SCHEMBL11192874 | 0.86 | SLC6A4 (0.66) | SLC6A4PDE3BPDE3ANR3C1PGR | |
| Water SCHEMBL11200345 | 0.85 | NR3C1 (0.76) | SLC6A4PDE3BPDE3ANR3C1PGR | |
| SCHEMBL11197536 | 0.85 | NR3C1 (0.64) | SLC6A4PDE3BPDE3ANR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | claimed |
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |