Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300753 | 1.00 | MAPT (0.50) | MAPTHDAC8HDAC6GAAHDAC3 | |
| SCHEMBL13769293 | 0.94 | NPY5R (0.47) | MAPTHDAC8HDAC6GAAHDAC3 | |
| SCHEMBL29196025 | 0.93 | ESR2 (0.45) | MAPTHDAC8HDAC6GAAHDAC3 | |
| SCHEMBL1335958 | 0.92 | NPY5R (0.60) | MAPTHDAC8HDAC6GAAHDAC3 | |
| SCHEMBL11199863 | 0.92 | NPY5R (0.60) | MAPTHDAC8HDAC6GAAHDAC3 | |
| SCHEMBL13769496 | 0.91 | NOTUM (0.44) | MAPTHDAC8HDAC6GAAHDAC3 | |
| SCHEMBL6352246 | 0.90 | MAPT (0.49) | MAPTHDAC8HDAC6GAAHDAC3 | |
| SCHEMBL4820760 | 0.90 | MAPT (0.62) | MAPTHDAC8HDAC6GAAHDAC3 | |
| SCHEMBL28690383 | 0.89 | NPY5R (0.57) | MAPTHDAC8HDAC6GAAHDAC3 | |
| SCHEMBL9418572 | 0.88 | MAPT (0.46) | MAPTHDAC8HDAC6GAAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072575-A1 | N,N'-diphenyl-p-phenylene diamines, method for their production and their use as stabilisers for organic materials | Chemische Werke Lowi GmbH (DE) | 1983-02-23 | — | — | EP | disclosed |