SCHEMBL4820760

SCHEMBL4820760

Cc1ccc(Nc2ccc(C3CCCCC3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
LMNA P02545 3/20 0.62
ALDH1A1 P00352 2/20 0.62
TP53 P04637 1/20 0.62
ATM Q13315 1/20 0.62
HPGD P15428 1/20 0.47
SLC18A3 Q16572 1/20 0.46
HTT P42858 2/20 0.46
XBP1 P17861 1/20 0.46
RAB9A P51151 5/20 0.45
P2RX3 P56373 1/20 0.45
NPY5R Q15761 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
GAA P10253 1/20 0.44
DEGS1 O15121 1/20 0.44
NPC1 O15118 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11201092 0.90 MAPT (0.50) MAPTSMN1; SMN2LMNAALDH1A1TP53
SCHEMBL3300753 0.90 MAPT (0.50) MAPTSMN1; SMN2LMNAALDH1A1TP53
SCHEMBL346325 0.88 LMNA (0.59) MAPTSMN1; SMN2LMNAALDH1A1TP53
SCHEMBL28722738 0.88 LMNA (0.59) MAPTSMN1; SMN2LMNAALDH1A1TP53
SCHEMBL8025878 0.88 LMNA (0.59) MAPTSMN1; SMN2LMNAALDH1A1TP53
SCHEMBL3295852 0.87 MAPT (0.50) MAPTSMN1; SMN2LMNAALDH1A1TP53
SCHEMBL43080 0.85 SLC18A3 (0.56) MAPTSMN1; SMN2LMNAALDH1A1TP53
SCHEMBL13769293 0.84 NPY5R (0.47) MAPTSMN1; SMN2LMNAALDH1A1TP53
SCHEMBL29196025 0.83 ESR2 (0.45) MAPTSMN1; SMN2LMNAALDH1A1TP53
SCHEMBL1335958 0.82 NPY5R (0.60) MAPTSMN1; SMN2LMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7390598-B2 Photoreceptor with three-layer photoconductive layer XEROX CORPORATION (US) 2008-06-24 US claimed
US-20060292466-A1 Photoreceptor with three-layer photoconductive layer XEROX CORPORATION (US) 2006-12-28 US claimed
EP-4174055-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2023-05-03 EP disclosed
CN-108947898-B Organic photoelectric functional material and application thereof 南京工业大学 2021-11-05 CN disclosed
EP-3544984-B1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
CN-108690091-B Iridium complex and preparation method and application thereof 南京工业大学 2020-09-01 CN disclosed
CN-108276450-B Aryl-substituted tetradentate ligand coordinated platinum complex and synthesis method and application thereof 南京工业大学 2020-08-21 CN disclosed
CN-108299510-B Iridium complex containing aza-arene auxiliary ligand and preparation method and application thereof 南京工业大学 2020-06-05 CN disclosed
WO-2016096069-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-06-23 WO disclosed
US-20140299864-A1 POLYMERS CONTAINING THERMALLY DISSOCIABLE AND SOLUBLE GROUPS AND THE USE OF SUCH POLYMERS AS ORGANIC ELECTROLUMINESCENT MATERIALS MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-09 US disclosed
US-20140299864-A1 POLYMERS CONTAINING THERMALLY DISSOCIABLE AND SOLUBLE GROUPS AND THE USE OF SUCH POLYMERS AS ORGANIC ELECTROLUMINESCENT MATERIALS MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-09 US disclosed
US-8795849-B2 Polymers containing thermally dissociable and soluble groups and the use of such polymers as organic electroluminescent materials MITSUBISHI CHEMICAL CORPORATION (JP) 2014-08-05 US disclosed
US-8795849-B2 Polymers containing thermally dissociable and soluble groups and the use of such polymers as organic electroluminescent materials MITSUBISHI CHEMICAL CORPORATION (JP) 2014-08-05 US disclosed
US-20110192464-A1 POLYMER, LUMINESCENT-LAYER MATERIAL, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT, SOLAR CELL ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING EACH OBTAINED USING THESE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-11 US disclosed
US-7390598-B2 Photoreceptor with three-layer photoconductive layer XEROX CORPORATION (US) 2008-06-24 US disclosed
US-20070059616-A1 Coated substrate for photoreceptor XEROX CORPORATION (US) 2007-03-15 US disclosed
US-20060292466-A1 Photoreceptor with three-layer photoconductive layer XEROX CORPORATION (US) 2006-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110192464-A1 POLYMER, LUMINESCENT-LAYER MATERIAL, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT, SOLAR CELL ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING EACH OBTAINED USING THESE LEF1, EPCAM, EBPL MAPT 328/4885SMN1; SMN2 2613/4885LMNA 322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.