Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 5/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 3/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | MTAP | Q13126 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237560 | 0.85 | PNP (0.58) | PNPHIF1AMTAP | |
| SCHEMBL3304855 | 0.85 | PNP (0.58) | PNPHIF1AMTAP | |
| SCHEMBL11194201 | 0.82 | PNP (0.47) | PNPHIF1ASLC5A2SMN1; SMN2MTAP | |
| SCHEMBL3305072 | 0.78 | PNP (0.80) | PNP | |
| SCHEMBL3305081 | 0.78 | PNP (0.80) | PNP | |
| SCHEMBL11199309 | 0.76 | HIF1A (0.49) | HIF1APYGLSLC5A2 | |
| SCHEMBL11195779 | 0.76 | HIF1A (0.44) | HIF1APYGLSLC5A2 | |
| SCHEMBL11422145 | 0.72 | HIF1A (0.47) | HIF1APYGLKDM4EGMNNLMNA | |
| SCHEMBL10858597 | 0.72 | PNP (0.53) | PNPHIF1APYGLSLC5A2KDM4E | |
| SCHEMBL2509842 | 0.71 | PNP (0.54) | PNPPYGLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071227-A1 | Anti-leukemic beta-glycosyl C-nucleosides | Sloan-Kettering Institute For Cancer Research (US) | 1983-02-09 | — | — | EP | claimed |