Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 5/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.40 |
| ▸ | MTAP | Q13126 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201279 | 0.82 | PNP (0.50) | PNPHIF1ASLC5A2MTAPSMN1; SMN2 | |
| SCHEMBL31237560 | 0.82 | PNP (0.58) | PNPHIF1AMTAP | |
| SCHEMBL3304855 | 0.82 | PNP (0.58) | PNPHIF1AMTAP | |
| SCHEMBL10807053 | 0.78 | HIF1A (0.46) | HIF1ASLC5A2TP53SMN1; SMN2ADK | |
| SCHEMBL3902751 | 0.78 | HIF1A (0.41) | HIF1ASLC5A2TP53SMN1; SMN2ADK | |
| SCHEMBL3902741 | 0.78 | HIF1A (0.41) | HIF1ASLC5A2TP53SMN1; SMN2ADK | |
| SCHEMBL3305081 | 0.75 | PNP (0.80) | PNP | |
| SCHEMBL3305072 | 0.75 | PNP (0.80) | PNP | |
| Ribose (Furanose) SCHEMBL5179410 | 0.71 | TP53 (0.61) | HIF1ATP53SMN1; SMN2 | |
| SCHEMBL11194197 | 0.71 | PYGL (0.38) | PNPHIF1ASLC5A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071227-A1 | Anti-leukemic beta-glycosyl C-nucleosides | Sloan-Kettering Institute For Cancer Research (US) | 1983-02-09 | — | — | EP | claimed |