Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201364 | 1.00 | GAA (0.43) | GAAALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL11201360 | 1.00 | GAA (0.43) | GAAALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL10729178 | 0.89 | GAA (0.47) | GAAALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL11197041 | 0.84 | GAA (0.35) | GAAALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL11214720 | 0.84 | GAA (0.35) | GAAALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL11214723 | 0.84 | GAA (0.35) | GAAALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL10735034 | 0.83 | ALDH1A1 (0.44) | GAAALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL10730744 | 0.83 | ALDH1A1 (0.44) | GAAALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL11004360 | 0.78 | GAA (0.36) | GAAALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL10743172 | 0.78 | GAA (0.36) | GAAALDH1A1MAPTL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074599-A1 | 5,6-cis-Carbapenem derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-03-23 | — | — | EP | disclosed |