Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.50 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.50 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205360 | 0.92 | CYP3A4 (0.66) | MAPK1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL11763305 | 0.89 | CYP3A4 (0.58) | MAPK1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL11758464 | 0.89 | MAPK1 (0.58) | MAPK1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL11760199 | 0.88 | MAPK1 (0.53) | MAPK1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL8153584 | 0.86 | MAPK1 (0.51) | MAPK1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL11522680 | 0.86 | MAPK1 (0.54) | MAPK1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL11765814 | 0.86 | MAPK1 (0.54) | MAPK1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL9345956 | 0.85 | CYP3A4 (0.56) | MAPK1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL10815711 | 0.83 | MAPK1 (0.50) | MAPK1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL11643284 | 0.82 | CYP3A4 (0.52) | MAPK1CYP3A4TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31227-E | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| US-RE31226-E | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-05-03 | — | — | US | disclosed |