SCHEMBL1120140

SCHEMBL1120140

Brc1ccc2ccccc2c1.[MgH2]

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.94
ALDH1A1 P00352 2/20 0.54
KDM4E B2RXH2 1/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
KMT2A Q03164 1/20 0.54
CYP1A2 P05177 5/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CYP3A4 P08684 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
ALOX12 P18054 1/20 0.44
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
PTPN1 P18031 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154221 0.97 CYP2A6 (1.00) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL29485684 0.97 CYP2A6 (1.00) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL29002798 0.94 CYP2A6 (0.94) CYP2A6ALDH1A1KDM4EMEN1MAPT
Benzene SCHEMBL27861653 0.94 CYP2A6 (0.94) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL22909955 0.94 CYP2A6 (0.94) CYP2A6ALDH1A1KDM4EMEN1MAPT
Methyl Alcohol SCHEMBL28320856 0.90 CYP2A6 (0.85) CYP2A6ALDH1A1KDM4EMEN1MAPT
Formaldehyde SCHEMBL28823619 0.90 CYP2A6 (0.85) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL17849081 0.89 CYP2A6 (0.84) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL29681779 0.89 CYP2A6 (0.84) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL1304424 0.89 CYP2A6 (0.84) CYP2A6ALDH1A1KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768733-B Aryl cyclic ammonium salt arylation and silicon-based method 中国科学技术大学 2025-05-23 CN claimed
CN-119859156-A Boron-nitrogen organic compound, preparation method and application thereof, composition and photoelectric device 广东聚华印刷显示技术有限公司 2025-04-22 CN claimed
CN-118908996-A A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond 烟台大学 2024-11-08 CN claimed
CN-116768733-A Aryl cyclic ammonium salt arylation and silicon-based method 中国科学技术大学 2023-09-19 CN claimed
WO-2023124996-A1 SULFUR-CONTAINING CHIRAL BRIDGED METALLOECENE COMPOUND, PREPARATION THEREOF, AND APPLICATION 中国石油天然气股份有限公司 2023-07-06 WO claimed
CN-108409764-B Organic photosensitizer capable of forming C-X bond by concerted catalysis with metallic nickel and synthetic method thereof 陕西师范大学 2020-07-28 CN claimed
CN-110759945-A Preparation method of phosphine chiral center sodium salt 南京理工大学 2020-02-07 CN claimed
CN-100548950-C Process for preparing esters and ethers of probucol and derivatives thereof ATHEROGENICS INC (US) 2009-10-14 CN claimed
CN-1759084-A Process for preparing esters and ethers of probucol and derivatives thereof ATHEROGENICS INC (US) 2006-04-12 CN claimed
CN-118908996-A A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond 烟台大学 2024-11-08 CN disclosed
CN-117230123-A Method for biosynthesis of 2- (naphthalene-2-yl) ethanol by using saccharomyces cerevisiae 江南大学 2023-12-15 CN disclosed
CN-116410238-A Sulfur-containing chiral bridged metallocene compound, and preparation and application thereof 中国石油天然气股份有限公司 2023-07-11 CN disclosed
WO-2023124996-A1 SULFUR-CONTAINING CHIRAL BRIDGED METALLOECENE COMPOUND, PREPARATION THEREOF, AND APPLICATION 中国石油天然气股份有限公司 2023-07-06 WO disclosed
CN-108373416-B Method for synthesizing diarylamine by photo/nickel concerted catalysis 陕西师范大学 2020-11-17 CN disclosed
EP-0722448-A1 O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY MERCK & CO. INC. (US) 1996-07-24 EP disclosed
US-5532248-A O-aryl,O-alkyl, and O-alkenyl-macrolides having immunosuppressive activity MERCK CO., INC. (US) 1996-07-02 US disclosed
WO-1995009857-A1 O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY MERCK & CO., INC. (US) 1995-04-13 WO disclosed
CN-1082035-A The inhibitors of hiv protease that is used for the treatment of AIDS LILLY CO ELI (US) 1994-02-16 CN disclosed
EP-0558321-A1 Antivirally active N-cycloalkyl alkanol compounds SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1993-09-01 EP disclosed
US-4048330-A Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia SYNTEX CORPORATION (US) 1977-09-13 US disclosed