SCHEMBL154221

SCHEMBL154221

Brc1ccc2ccccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 1.00
ALDH1A1 P00352 2/20 0.56
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 1/20 0.56
MAPT P10636 1/20 0.56
KMT2A Q03164 1/20 0.56
CYP1A2 P05177 5/20 0.48
CYP2C19 P33261 1/20 0.48
HTT P42858 1/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CYP3A4 P08684 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
ALOX12 P18054 1/20 0.47
CYP11B1 P15538 1/20 0.45
CYP11B2 P19099 1/20 0.45
DHODH Q02127 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29485684 1.00 CYP2A6 (1.00) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL29002798 0.97 CYP2A6 (0.94) CYP2A6ALDH1A1KDM4EMEN1MAPT
Benzene SCHEMBL27861653 0.97 CYP2A6 (0.94) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL22909955 0.97 CYP2A6 (0.94) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL1120140 0.97 CYP2A6 (0.94) CYP2A6ALDH1A1KDM4EMEN1MAPT
Methyl Alcohol SCHEMBL28320856 0.92 CYP2A6 (0.85) CYP2A6ALDH1A1KDM4EMEN1MAPT
Formaldehyde SCHEMBL28823619 0.92 CYP2A6 (0.85) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL17849081 0.92 CYP2A6 (0.84) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL1304424 0.92 CYP2A6 (0.84) CYP2A6ALDH1A1KDM4EMEN1MAPT
SCHEMBL30792510 0.92 CYP2A6 (0.84) CYP2A6ALDH1A1KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5117 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115283129-B Efficient enrichment method for low-grade fluorite ore 中国地质科学院郑州矿产综合利用研究所 2025-05-30 CN claimed
CN-119613322-A Circularly polarized luminescent material and preparation method thereof 杭州惠臣科技有限公司 2025-03-14 CN claimed
CN-118955262-A Direct cross-coupling method of pyridine ester and aryl bromide 南京工业大学 2024-11-15 CN claimed
CN-118437307-A Application of amorphous carbon material and synthetic method of poly-deuterated aromatic compound 无锡绿能电合科技有限公司 2024-08-06 CN claimed
CN-112771684-B Ink composition for manufacturing organic semiconductor device 株式会社大赛璐 2024-07-12 CN claimed
CN-118006179-B Impact-resistant water-based automobile paint and preparation method thereof 合肥旭阳铝颜料有限公司 2024-07-05 CN claimed
CN-118176293-A SIRPalpha-deficient macrophages for the treatment of cancer 佐治亚州立大学研究基金会公司 2024-06-11 CN claimed
CN-118164887-A Long wavelength lipid drop fluorescent probe with large Stokes shift, synthesis and application 中国科学院大连化学物理研究所 2024-06-11 CN claimed
CN-118006179-A Impact-resistant water-based automobile paint and preparation method thereof 合肥旭阳铝颜料有限公司 2024-05-10 CN claimed
CN-117843427-A Synthesis method of axisymmetric dinaphthylcyclopentene fused tetraphenyl 内蒙古大学 2024-04-09 CN claimed
US-5759734-A Method of generating simulated photographic-quality images on luminescent melt-formed backing substrates XEROX CORPORATION (US) 1998-06-02 US claimed
CN-1037115-C Method for raising cyaniding extraction rate and recovery percent of carbonaceous gold ore by compound inhibitor UNIV SICHUAN UNION (CN) 1998-01-21 CN claimed
EP-0396943-B1 Optical storage medium and storage process NIPPON TELEGRAPH & TELEPHONE (JP) 1995-07-05 EP claimed
EP-0406769-B1 PROCESS FOR THE PREPARATION OF 2-CHLORO- , RESP. 2-BROMONAPHTHALENE HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-25 EP claimed
US-5124944-A OPTICAL STORAGE MEDIUM AND STORAGE PROCESS NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-06-23 US claimed
US-5043493-A Isomerization using zeolite catalyst HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-27 US claimed
EP-0406769-A1 Process for the preparation of 2-chloro- , resp. 2-bromonaphthalene HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-09 EP claimed
US-4631151-A REACTING DI(HALOACYL)PEROXIDE WITH AROMATIC HYDROCARBON NIPPON OIL & FARS CO., LTD. (JP) 1986-12-23 US claimed
US-4435222-A HALOGENATED NAPHTHALENES AND BIPHENYLS FOLLOWED BY ALUMUNUM HALIDES PHILLIPS PETROLEUM COMPANY (US) 1984-03-06 US claimed
US-4082817-A HALOGENATED AROMATIC HYDROCARBON SOLVENT, GEL-FREE JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1978-04-04 US claimed