SCHEMBL11201422

SCHEMBL11201422

Cc1ccccc1Cc1ccccc1CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.52
ALDH1A1 P00352 1/20 0.46
TAAR1 Q96RJ0 2/20 0.45
HTR1A P08908 1/20 0.43
DRD2 P14416 1/20 0.43
ATM Q13315 1/20 0.42
ABCB1 P08183 1/20 0.41
DAO P14920 1/20 0.41
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ATP4A P20648 1/20 0.40
ATP4B P51164 1/20 0.40
DRD4 P21917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1587756 0.87 TAAR1 (0.58) HTR2AALDH1A1TAAR1HTR1ADRD2
SCHEMBL7192027 0.87 HTR2A (0.54) HTR2AALDH1A1TAAR1DRD2SMN1; SMN2
SCHEMBL30173449 0.87 TAAR1 (0.58) HTR2AALDH1A1TAAR1HTR1ADRD2
SCHEMBL2140999 0.87 HTR2A (0.54) HTR2AALDH1A1TAAR1DRD2SMN1; SMN2
SCHEMBL2996327 0.85 HTR2A (0.68) HTR2AALDH1A1TAAR1HTR1ADRD2
SCHEMBL9741301 0.83 CALM1 (0.55) HTR2AALDH1A1TAAR1DRD2SMN1; SMN2
SCHEMBL275838 0.83 CALM1 (0.55) HTR2AALDH1A1TAAR1DRD2SMN1; SMN2
SCHEMBL29940610 0.83 CALM1 (0.55) HTR2AALDH1A1TAAR1DRD2SMN1; SMN2
SCHEMBL11200954 0.82 TAAR1 (0.54) ALDH1A1TAAR1LMNA
SCHEMBL12506263 0.81 TAAR1 (0.60) ALDH1A1TAAR1HTR1ADRD2ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US disclosed