Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762457 | 0.72 | — | — | |
| SCHEMBL14613499 | 0.70 | MAOA (0.38) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15871031 | 0.69 | TRIM24 (0.65) | TRIM24TRIM33KMT2AMAPTMEN1 | |
| SCHEMBL5641557 | 0.68 | — | — | |
| SCHEMBL6762199 | 0.67 | TRIM24 (0.52) | TRIM24TRIM33KMT2AMAPTMEN1 | |
| Pyrrole SCHEMBL9109239 | 0.66 | TRIM24 (0.80) | TRIM24TRIM33KMT2AMAPTMEN1 | |
| SCHEMBL18917594 | 0.66 | GRIN2D (0.46) | TRIM24TRIM33KMT2AMAPTMEN1 | |
| SCHEMBL2725558 | 0.65 | — | — | |
| SCHEMBL17266502 | 0.65 | — | — | |
| SCHEMBL5642059 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068617-A1 | Derivatives of clavulanic acid, a process for their preparation and their use | BEECHAM GROUP PLC (GB) | 1983-01-05 | — | — | EP | disclosed |