Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18791148 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1MAPT | |
| SCHEMBL1969445 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1MAPT | |
| SCHEMBL5432030 | 0.81 | ADORA2A (0.40) | HSP90AB1ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL6015590 | 0.78 | HSP90AB1 (0.40) | HSP90AB1ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL11200109 | 0.77 | SELE (0.49) | ADORA2AADORA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11197383 | 0.77 | ADORA2A (0.39) | HTTHSP90AB1ADORA2AADORA1 | |
| SCHEMBL20668002 | 0.75 | HSP90AB1 (0.35) | HSP90AB1ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL22727737 | 0.75 | CNR1 (0.35) | HSP90AB1ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL5467748 | 0.75 | CSNK2A2 (0.36) | KDM4EALDH1A1MAPT | |
| SCHEMBL2305098 | 0.75 | ABCB1 (0.50) | HSP90AB1ADORA2AADORA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |