SELE — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL609962	1.00	20/20
SCHEMBL2742900	0.71	19/20
SCHEMBL806655	0.52	19/20
SCHEMBL806988	0.52	19/20
SCHEMBL2009152	0.74	18/20
SCHEMBL2009153	0.74	18/20
SCHEMBL806972	0.61	18/20
SCHEMBL806985	0.60	18/20
SCHEMBL806971	0.60	18/20
SCHEMBL806979	0.60	18/20
SCHEMBL806983	0.59	18/20
SCHEMBL806990	0.58	18/20
SCHEMBL806639	0.58	18/20
SCHEMBL806866	0.57	18/20
SCHEMBL806640	0.57	18/20
SCHEMBL807222	0.57	18/20
SCHEMBL806991	0.57	18/20
SCHEMBL806634	0.56	18/20
SCHEMBL806873	0.56	18/20
SCHEMBL806637	0.55	18/20

Clinical trials — most relevant to SELE by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Atorvastatin in Acute Stroke Treatment	PHASE4	COMPLETED
Metabolic Impact Assessment of Tenofovir Disoproxil Fumarate on Non-HIV-1 Infected Healthy Adult Male Volunteers	PHASE4	COMPLETED
Effects of Anemia Correction on Vascular and Monocyte Function in Renal Transplant Recipients	PHASE4	COMPLETED
Role of Alpha-lipoic Acid in Diabetes Melitus Type 1	PHASE3	UNKNOWN
Crizanlizumab for Treating COVID-19 Vasculopathy	PHASE2	COMPLETED
E-Selectin Nasal Instillation to Prevent Secondary Stroke	PHASE1	WITHDRAWN
PK and PD Responses to Oral L-Citrulline in Patients With Sickle Cell Disease	PHASE1	UNKNOWN
Investigation of the Influence of Gender on Cardiovascular Function	EARLY_PHASE1	COMPLETED
Endothelial Dysfunction and Selenium Status in Children With Acute Systemic Inflammatory Response	nan	COMPLETED
Dynamic Changes in the Levels of sCD62L and SPARC in Chronic Myeloid Leukemia Patients During Imatinib Treatment	nan	COMPLETED
Brain Activity and Oxygenation Inflammatory Bowel Disease (IBD) Patients	nan	UNKNOWN
Role of Endothelial Cells in the Pathogenesis of Chronic Urticaria.	nan	UNKNOWN
Abdominal Aortic Aneurysm Surgery and Thrombosis	nan	COMPLETED
Assessment of Platelet Storage Lesion(PSL)in Platelet Concentrates	nan	UNKNOWN
Infection, Sepsis and Meningitis in Surinamese Neonates	nan	COMPLETED
ITGA2b and SELP Expression in Cancer Pancreas and Biliary Tract Cancer	nan	UNKNOWN
Common Variants in Candidate Genes and Premature MI Risk	nan	COMPLETED
Endothelial Microparticles as a Biomarker for Diagnosis and Prognosis in Early Sepsis	nan	COMPLETED
Exercise and Cycle Ergometry Post TKA - A Randomized Controlled Trial	nan	COMPLETED
Multi-Analyte, Genetic, and Thrombogenic Markers of Atherosclerosis	nan	UNKNOWN
Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria	nan	COMPLETED
Noninvasive Evaluation of Cardiac Allograft Vasculopathy	nan	WITHDRAWN
Noninvasive Predictors of Transplant Vasculopathy	nan	WITHDRAWN
Impact of Combination of Clopidogrel With Aspirin on Postoperative Bleeding in Coronary Surgical Patients	nan	COMPLETED
Examining the Link Between Heart Disease and HIV Infection in Women	nan	COMPLETED
A Study to Identify Biomarkers of Hypoglycaemia in Patients With Type 2 Diabetes	nan	COMPLETED
Efficacy of Early Short-term Training on Thrombogenesis in Patients Following Coronary Bypass Surgery	nan	COMPLETED
Pilot Study of Bevacizumab (Avastin) in Patients With Septic Shock	nan	WITHDRAWN
The Relationship of Change of Dendritic Cells Fractalkine and P-selectin Patients With Acute Myocardial Infarction	nan	COMPLETED
Study of the Vascular Response to Percutaneous Coronary Intervention in Patients With Non-ST-elevation Acute Coronary Syndromes Using Intravascular Blood Sampling	nan	WITHDRAWN

Related proteins — ESM-2 sequence neighbours (a SELE binder may also engage these)

Protein	Name	Similarity
P27113	—	0.999	P27113 →
P98110	—	0.997	P98110 →
Q95LG1	—	0.997	Q95LG1 →
P33730	—	0.996	P33730 →
P98105	—	0.994	P98105 →
Q00690	—	0.994	Q00690 →
P42201	—	0.992	P42201 →
P98106	—	0.991	P98106 →
P98109	—	0.991	P98109 →
P98107	—	0.990	P98107 →
Q01102	—	0.989	Q01102 →
Q95198	—	0.987	Q95198 →
SELP	P-selectin	0.986	landscape →
P30836	—	0.984	P30836 →
Q28768	—	0.981	Q28768 →
SELL	L-selectin	0.981	landscape →
Q95237	—	0.981	Q95237 →
P98131	—	0.978	P98131 →
P20023	—	0.977	P20023 →
P08607	—	0.977	P08607 →
P35952	—	0.975	P35952 →
Q9ET61	—	0.974	Q9ET61 →
P01131	—	0.974	P01131 →
Q95235	—	0.973	Q95235 →
Q7TSY4	—	0.972	Q7TSY4 →
P35951	—	0.971	P35951 →
Q60736	—	0.971	Q60736 →
P35950	—	0.971	P35950 →
P78504	—	0.970	P78504 →
Q63135	—	0.970	Q63135 →