Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP4 | P49662 | 1/20 | 0.35 |
| ▸ | CASP5 | P51878 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206049 | 0.87 | P2RY12 (0.50) | P2RY12SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL11202546 | 0.86 | P2RY12 (0.49) | P2RY12SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL11203621 | 0.82 | P2RY12 (0.49) | P2RY12SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL11204811 | 0.82 | P2RY12 (0.47) | P2RY12SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL11197610 | 0.80 | P2RY12 (0.52) | P2RY12SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL11198078 | 0.80 | P2RY12 (0.48) | P2RY12SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL11197165 | 0.79 | P2RY12 (0.49) | P2RY12SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL11199721 | 0.78 | P2RY12 (0.50) | P2RY12SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL11205948 | 0.76 | P2RY12 (0.48) | P2RY12SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL11203169 | 0.75 | P2RY12 (0.48) | P2RY12SMN1; SMN2KDM4ETMIGD3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |