Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP5 | P51878 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197610 | 0.95 | P2RY12 (0.52) | P2RY12KDM4ESMN1; SMN2TMIGD3RAB9A | |
| SCHEMBL11205063 | 0.86 | KDM4E (0.47) | P2RY12KDM4ESMN1; SMN2TMIGD3RAB9A | |
| SCHEMBL11205731 | 0.84 | KDM4E (0.46) | P2RY12KDM4EALDH1A1APAF1POLB | |
| SCHEMBL11199830 | 0.83 | HTR6 (0.61) | P2RY12KDM4ESMN1; SMN2TMIGD3RAB9A | |
| SCHEMBL11200264 | 0.83 | HTR6 (0.48) | P2RY12KDM4ESMN1; SMN2TMIGD3RAB9A | |
| SCHEMBL11203412 | 0.81 | HTR6 (0.49) | P2RY12KDM4ESMN1; SMN2TMIGD3RAB9A | |
| SCHEMBL11206143 | 0.80 | KDM4E (0.49) | P2RY12KDM4ESMN1; SMN2TMIGD3RAB9A | |
| SCHEMBL11197283 | 0.80 | SMN1; SMN2 (0.46) | P2RY12KDM4ESMN1; SMN2TMIGD3RAB9A | |
| SCHEMBL11197408 | 0.79 | KDM4E (0.52) | P2RY12KDM4ESMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL11199721 | 0.79 | P2RY12 (0.50) | P2RY12KDM4ESMN1; SMN2TMIGD3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |