Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400809 | 0.81 | CYP2C19 (0.54) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL12897248 | 0.79 | KMT2A (0.55) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL13987057 | 0.79 | KMT2A (0.47) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL27908862 | 0.78 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL2912486 | 0.78 | KMT2A (0.46) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL29110955 | 0.78 | MIF (0.50) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL28421004 | 0.75 | KMT2A (0.50) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL5761972 | 0.74 | — | — | |
| SCHEMBL5763413 | 0.74 | — | — | |
| SCHEMBL10938332 | 0.74 | ALDH1A1 (0.48) | KMT2AALDH1A1MEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084941-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-03 | — | — | EP | disclosed |