Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC42 | P60953 | 3/20 | 0.41 |
| ▸ | RAC1 | P63000 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198773 | 0.96 | CDC42 (0.40) | CDC42RAC1NPC1PTGS1PTGS2 | |
| SCHEMBL11198826 | 0.82 | CHRNA1 (0.38) | NPC1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11195833 | 0.79 | CHRNA1 (0.38) | NPC1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11194044 | 0.78 | PTGS2 (0.65) | CDC42RAC1NPC1PTGS1PTGS2 | |
| SCHEMBL9088673 | 0.78 | CDC42 (0.60) | CDC42RAC1NPC1PTGS1PTGS2 | |
| SCHEMBL11197740 | 0.77 | PTGS2 (0.64) | CDC42RAC1NPC1PTGS1PTGS2 | |
| SCHEMBL11201558 | 0.77 | PTGS2 (0.64) | CDC42RAC1NPC1PTGS1PTGS2 | |
| SCHEMBL11206957 | 0.77 | PTGS2 (0.64) | CDC42RAC1NPC1PTGS1PTGS2 | |
| SCHEMBL11192941 | 0.76 | CDC42 (0.49) | CDC42RAC1NPC1PTGS1PTGS2 | |
| SCHEMBL11198770 | 0.75 | PTGS2 (0.64) | CDC42RAC1NPC1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410534-A | 3-Substituted-5,6,7,8-tetrahydropyrrolo[1,2-a]-pyridine-and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]-azepine carboxylic acid derivatives useful as blood platelet aggregation inhibitors | SYNTEX (U.S.A.) INC. (US) | 1983-10-18 | — | — | US | disclosed |