Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 15/20 | 0.55 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493160 | 0.81 | TBXAS1 (0.75) | TBXAS1EGLN3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3225053 | 0.80 | TBXAS1 (0.79) | TBXAS1 | |
| SCHEMBL3468871 | 0.80 | TBXAS1 (0.79) | TBXAS1 | |
| SCHEMBL9348072 | 0.80 | TBXAS1 (0.79) | TBXAS1 | |
| SCHEMBL3795568 | 0.80 | TBXAS1 (0.79) | TBXAS1 | |
| SCHEMBL6265445 | 0.80 | TBXAS1 (0.79) | TBXAS1 | |
| SCHEMBL4684954 | 0.80 | TBXAS1 (0.79) | TBXAS1 | |
| Bromide SCHEMBL18941391 | 0.80 | TBXAS1 (0.72) | TBXAS1EGLN3 | |
| SCHEMBL9001 | 0.79 | — | — | |
| Bromide SCHEMBL28424328 | 0.78 | TBXAS1 (0.76) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033432-B1 | THERAPEUTIC COMPOSITION BASED ON IMIDAZOLES, ESPECIALLY FOR THE TREATMENT OF THROMBOSES; IMIDAZOLES AND PROCESS FOR THEIR PREPARATION | LABORATOIRES CHAUVIN-BLACHE Société dite: (FR) | 1983-09-28 | — | — | EP | claimed |
| EP-0033432-A1 | Therapeutic composition based on imidazoles, especially for the treatment of thromboses; imidazoles and process for their preparation | LABORATOIRES CHAUVIN-BLACHE Société dite: (FR) | 1981-08-12 | — | — | EP | claimed |
| EP-0033432-B1 | THERAPEUTIC COMPOSITION BASED ON IMIDAZOLES, ESPECIALLY FOR THE TREATMENT OF THROMBOSES; IMIDAZOLES AND PROCESS FOR THEIR PREPARATION | LABORATOIRES CHAUVIN-BLACHE Société dite: (FR) | 1983-09-28 | — | — | EP | disclosed |
| EP-0033432-A1 | Therapeutic composition based on imidazoles, especially for the treatment of thromboses; imidazoles and process for their preparation | LABORATOIRES CHAUVIN-BLACHE Société dite: (FR) | 1981-08-12 | — | — | EP | disclosed |