Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730067 | 0.91 | HTT (0.38) | ALDH1A1MAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL10735072 | 0.89 | HTR2A (0.37) | ALDH1A1MAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL10734182 | 0.89 | HTR2A (0.37) | ALDH1A1MAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL10346252 | 0.87 | ALDH1A1 (0.34) | ALDH1A1MAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL9670137 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL11197041 | 0.84 | GAA (0.35) | ALDH1A1MAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL11214723 | 0.84 | GAA (0.35) | ALDH1A1MAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL11214720 | 0.84 | GAA (0.35) | ALDH1A1MAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL10493918 | 0.84 | ALDH1A1 (0.37) | ALDH1A1MAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL10556308 | 0.83 | HTR2A (0.39) | ALDH1A1MAPTPOLBSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074599-A1 | 5,6-cis-Carbapenem derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-03-23 | — | — | EP | disclosed |