Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.39 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.39 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196149 | 0.89 | KDM4E (0.46) | GPR3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11196099 | 0.87 | GPR3 (0.61) | GPR3ALDH1A1HPGDKDM4EMEN1 | |
| Benzonaphthyridine SCHEMBL30897319 | 0.78 | GPR3 (1.00) | GPR3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4485428 | 0.78 | GPR3 (0.87) | GPR3ALDH1A1HPGDKDM4EHSD17B10 | |
| Benzonaphthyridine SCHEMBL29600756 | 0.78 | GPR3 (1.00) | GPR3ALDH1A1HPGDKDM4EHSD17B10 | |
| Benzonaphthyridine SCHEMBL51197 | 0.78 | GPR3 (1.00) | GPR3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11516837 | 0.74 | GPR3 (0.61) | GPR3ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14627008 | 0.74 | GPR3 (0.61) | GPR3ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL11517561 | 0.74 | GPR3 (0.61) | GPR3ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL38660962 | 0.74 | GPR3 (0.61) | GPR3ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369318-A | USING A BENZO-OR PYRIDO-CINNOLINES AS BLEACH CATALYST | CIBA-GEIGY LTD. (CH) | 1983-01-18 | — | — | US | disclosed |
| US-4266011-A | FUSED PYRIDAZINE CATALYST | CIBA-GEIGY AG (CH) | 1981-05-05 | — | — | US | disclosed |