Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 8/20 | 0.38 |
| ▸ | CA2 | P00918 | 8/20 | 0.38 |
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822786 | 0.91 | ATM (0.37) | TSHRCA1CA2EPHX1ADH1B | |
| SCHEMBL24829882 | 0.83 | TSHR (0.39) | TSHRCA1CA2CA9LPAR3 | |
| SCHEMBL16329381 | 0.79 | LPAR3 (0.39) | TSHRCA1CA2CA9LPAR3 | |
| SCHEMBL16278823 | 0.79 | CA1 (0.39) | TSHRCA1CA2CA9LPAR3 | |
| SCHEMBL11748915 | 0.78 | RECQL (0.41) | TSHRCA1CA2CA9LPAR3 | |
| SCHEMBL7918378 | 0.74 | CA1 (0.44) | TSHRCA1CA2CA9LPAR3 | |
| SCHEMBL7157641 | 0.74 | CA1 (0.44) | TSHRCA1CA2CA9LPAR3 | |
| SCHEMBL7927231 | 0.74 | CA1 (0.44) | TSHRCA1CA2CA9LPAR3 | |
| SCHEMBL4505591 | 0.74 | THRB (0.44) | TSHRCA1CA2CA9LPAR3 | |
| SCHEMBL7918384 | 0.74 | CA1 (0.44) | TSHRCA1CA2CA9LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036539-B1 | PROCESS FOR THE PREPARATION OF ACETALS OF METHYL GLYOXAL | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-07-27 | — | — | EP | disclosed |
| EP-0036539-A1 | Process for the preparation of acetals of methyl glyoxal | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-30 | — | — | EP | disclosed |