Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12069062 | 0.84 | ALDH1A1 (0.59) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL377477 | 0.84 | ALDH1A1 (0.56) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL3745815 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL2606333 | 0.82 | ALDH1A1 (0.59) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL70137 | 0.82 | ALDH1A1 (0.59) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL71088 | 0.81 | ALDH1A1 (0.60) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL377372 | 0.81 | ALDH1A1 (0.58) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL1812965 | 0.81 | ALDH1A1 (0.58) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL70179 | 0.81 | ALDH1A1 (0.58) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL69769 | 0.81 | ALDH1A1 (0.58) | ALDH1A1NPC1MAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092391-A2 | Novel piperidine derivatives and pharmaceutical compositions containing same | KYOWA HAKKO KOGYO CO., LTD (JP) | 1983-10-26 | — | — | EP | disclosed |