Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750167 | 0.76 | NOS1 (0.57) | NOS1ALDH1A1PBRM1DDX3XCYP3A4 | |
| SCHEMBL10884508 | 0.71 | NOS1 (0.47) | NOS1ALDH1A1PBRM1DDX3XCYP3A4 | |
| SCHEMBL9041395 | 0.69 | PBRM1 (0.53) | ALDH1A1PBRM1DDX3XCYP3A4CASP1 | |
| SCHEMBL19526913 | 0.67 | NOS1 (0.55) | NOS1ALDH1A1PBRM1DDX3XCYP3A4 | |
| SCHEMBL79078 | 0.66 | — | — | |
| SCHEMBL8128359 | 0.66 | CYP3A4 (0.58) | NOS1ALDH1A1CYP3A4CASP1RECQL | |
| SCHEMBL8652139 | 0.66 | CYP3A4 (0.58) | NOS1ALDH1A1CYP3A4CASP1RECQL | |
| SCHEMBL30681183 | 0.66 | NOS1 (0.53) | NOS1ALDH1A1PBRM1DDX3XNPC1 | |
| SCHEMBL28418792 | 0.66 | NOS1 (0.53) | NOS1ALDH1A1PBRM1DDX3XNPC1 | |
| SCHEMBL17980515 | 0.66 | CYP3A4 (0.48) | ALDH1A1PBRM1DDX3XCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |