⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3881741 | 0.97 | SOS1 (0.52) | — | |
| Iodide SCHEMBL22031615 | 0.97 | SOS1 (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL27616014 | 0.97 | SOS1 (0.52) | — | |
| Hydrochloric Acid SCHEMBL1992388 | 0.97 | SOS1 (0.52) | — | |
| SCHEMBL1157614 | 0.95 | SOS1 (0.50) | — | |
| SCHEMBL20528085 | 0.93 | SOS1 (0.48) | — | |
| SCHEMBL6961310 | 0.84 | SOS1 (0.45) | — | |
| SCHEMBL17280565 | 0.82 | — | — | |
| Succinic Acid SCHEMBL14244524 | 0.82 | SOS1 (0.40) | — | |
| SCHEMBL30660182 | 0.79 | SOS1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118512927-A | PEODT conductive nanofiltration membrane, preparation method and cleaning method thereof | 南京工业大学 | 2024-08-20 | — | — | CN | claimed |
| CN-118161994-A | PEODT conductive nanofiltration membrane, preparation method and cleaning method thereof | 南京工业大学 | 2024-06-11 | — | — | CN | claimed |
| US-20220033367-A1 | PRODRUGS OF 4-((1R, 3S)-6-CHLORO-3-PHENYL-2,3-DIHYDRO-1H-INDEN-1-Y)-1-,2,2-TRIMETHYLPIPERAZINE AND 4-((1R,3S)-6-CHLORO-3-(PHENYL-D5)-2,3-DIHYDRO-1H-INDEN-1YL)-2,2-DIMETHYL-1 (METHYL-D3)PIPERAZINE | H. LUNDBECK A/S (DK) | 2022-02-03 | — | — | US | claimed |
| EP-3891134-A1 | PRODRUGS OF 4-((1R,3S)-6-CHLORO-3-PHENYL-2,3-DIHYDRO-1H-INDEN-1-YL)-1,2,2-TRIMETHYLPIPERAZINE AND 4-((1/R,3S)-6-CHLORO-3-(PHENYL-D5)-2,3-DIHYDRO-1H-INDEN-1-YL)-2,2-DIMETHY-1-(METHYL-D3)PIPERAZINE | H. Lundbeck A/S (DK) | 2021-10-13 | — | — | EP | claimed |
| WO-2020114853-A1 | PRODRUGS OF 4-((1R,3S)-6-CHLORO-3-PHENYL-2,3-DIHYDRO-1H-INDEN-1-YL)-1,2,2-TRIMETHYLPIPERAZINE AND 4-((1/R,3S)-6-CHLORO-3-(PHENYL-D5)-2,3-DIHYDRO-1H-INDEN-1-YL)-2,2-DIMETHY-1-(METHYL-D3)PIPERAZINE | H. LUNDBECK A/S (DK) | 2020-06-11 | — | — | WO | claimed |
| CN-104583217-B | Substituted thiophene-fused and furan-fused oxazolopyrimidine-5- (6H) -one compounds | 达特神经科学(开曼)有限公司 | 2017-11-17 | — | — | CN | claimed |
| CN-104955796-B | 6-CHLORO-3-(PHENYL-D5)-INDEN-1-ONE AND USE THEREOF | H.隆德贝克有限公司 | 2017-05-24 | — | — | CN | claimed |
| EP-2861605-B1 | 6-Benzyl-6H-thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5-one derivatives as phosphodiesterase-1 (PDE-1) inhibitors for the treatment of e.g. neurological, cognitive and cardiovascular disorders | DART NEUROSCIENCE (CAYMAN) LTD (KY) | 2017-05-03 | — | — | EP | claimed |
| EP-2720989-B1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | LUNDBECK & CO AS H (DK) | 2016-08-10 | — | — | EP | claimed |
| US-9216961-B2 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | H. LUNDBECK A/S (DK) | 2015-12-22 | — | — | US | claimed |
| EP-2285377-A1 | METHOD FOR TREATING COGNITIVE DEFICITS | H. Lundbeck A/S (DK) | 2011-02-23 | — | — | EP | claimed |
| US-20100324291-A1 | PROCESSES FOR 4-((1R,3S)-6-CHLORO-3-PHENYLINDAN-1-YL)-1,2,2-TRIMETHYLPIPERAZINE OR A SALT THEREOF | H. LUNDBECK A/S (DK) | 2010-12-23 | — | — | US | claimed |
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | claimed |
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | claimed |
| EP-2014695-A1 | Aliphatic polyester polymer compositions and preparation method thereof | Industrial Technology Research Institut (TW) | 2009-01-14 | — | — | EP | claimed |
| US-20070155943-A1 | Aliphatic polyester polymer compositions and preparation method thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2007-07-05 | — | — | US | claimed |
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | claimed |
| US-20060128685-A1 | Pyrazole derivative | DAIICHI PHARMACEUTICAL CO., LTD., (JP) | 2006-06-15 | — | — | US | claimed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | claimed |
| EP-1591443-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-02 | — | — | EP | claimed |