Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27616014

CN1CCNCC1(C)C.N

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.52
SOS2 Q07890 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1120435 0.97
Iodide SCHEMBL22031615 0.95 SOS1 (0.52) SOS1SOS2
Hydrochloric Acid SCHEMBL3881741 0.95 SOS1 (0.52) SOS1SOS2
Hydrochloric Acid SCHEMBL1992388 0.95 SOS1 (0.52) SOS1SOS2
SCHEMBL1157614 0.92 SOS1 (0.50) SOS1SOS2
SCHEMBL20528085 0.90 SOS1 (0.48) SOS1SOS2
SCHEMBL6961310 0.82 SOS1 (0.45) SOS1SOS2
SCHEMBL17280565 0.80
Succinic Acid SCHEMBL14244524 0.80 SOS1 (0.40) SOS1SOS2
SCHEMBL30660182 0.77 SOS1 (0.41) SOS1SOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101450934-B Sulfonyl-derivatives as novel inhibitors of histone deacetylase JANSSEN PHARMACEUTICA NV 2012-10-10 CN disclosed
CN-101450934-A Sulfonyl-derivatives as novel inhibitors of histone deacetylase JANSSEN PHARMACEUTICA NV (BE) 2009-06-10 CN disclosed
CN-100445276-C Sulfonyl derivatives as histone deacetylase inhibitors JANSSEN PHARMACEUTICA NV (BE) 2008-12-24 CN disclosed
CN-1642931-A Sulfonyl derivatives as novel histone deacetylase inhibitors JANSSEN PHARMACEUTICA NV (BE) 2005-07-20 CN disclosed