Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14450469 | 0.79 | CES2 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL6494106 | 0.79 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL8893027 | 0.77 | CA12 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL30738439 | 0.77 | CHRM2 (0.50) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL11204657 | 0.77 | CHRM2 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL24784667 | 0.76 | BLM (0.48) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL29638790 | 0.76 | BLM (0.48) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL19396417 | 0.76 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL280516 | 0.76 | CA12 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL16297767 | 0.76 | CA12 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007572-B1 | PHARMACEUTICAL MIXTURES CONTAINING AN AMANTADINE COMPOUND | CIBA-GEIGY AG (CH) | 1983-04-27 | — | — | EP | claimed |