SCHEMBL11204686

SCHEMBL11204686

O=C1C(Cl)CCCC1(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11419954 0.84
SCHEMBL8678117 0.76 MEN1 (0.33)
SCHEMBL11358276 0.72
SCHEMBL11354143 0.68
SCHEMBL19784615 0.65
SCHEMBL8837698 0.64
SCHEMBL11773986 0.64
SCHEMBL186373 0.64 ALDH1A1 (0.30)
SCHEMBL10796302 0.63 CYP2C9 (0.31)
SCHEMBL21295306 0.61 KMT2A (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0036378-B1 PROCESS FOR THE PREPARATION OF CHLOROPHENOLS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-07-06 EP claimed
US-4351969-A Preparation of chlorophenols RHONE-POULENC INDUSTRIES (FR) 1982-09-28 US claimed
US-4166914-A Production of o-alkoxyphenols Van Winckel, Carl E. (CA) 1979-09-04 US claimed
US-4351969-A Preparation of chlorophenols RHONE-POULENC INDUSTRIES (FR) 1982-09-28 US disclosed
US-4268694-A HYDROLYSIS OF TETRAHALOCYCLOHEXANONE FISONS LIMITED (GB) 1981-05-19 US disclosed
US-4267378-A 2,2-Dialkoxy-6-chlorocyclohexanones Van Winckel, Carl E. (CA) 1981-05-12 US disclosed
US-4219505-A HALOGENATION OF A CYCLOHEXANOME WITH AN ORGANOPHOSPHOROUS CATALYST FISONS LIMITED (GB) 1980-08-26 US disclosed
US-4166914-A Production of o-alkoxyphenols Van Winckel, Carl E. (CA) 1979-09-04 US disclosed
US-3927106-A Preparation of tetrachlorocyclo-hexanone QO CHEMICALS, INC. 1975-12-16 US disclosed
US-3894087-A Method of producing 2,2,6-trichlorocyclo-hexanone and compositions thereof QO CHEMICALS, INC. 1975-07-08 US disclosed
US-3894087-A Method of producing 2,2,6-trichlorocyclo-hexanone and compositions thereof QO CHEMICALS, INC. 1975-07-08 US disclosed