Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225024 | 0.87 | KDM4E (0.32) | SMN1; SMN2 | |
| SCHEMBL11208194 | 0.83 | MAOB (0.47) | — | |
| SCHEMBL11208197 | 0.83 | MAOB (0.47) | — | |
| SCHEMBL11266744 | 0.83 | IDO1 (0.39) | IDO1 | |
| SCHEMBL11209273 | 0.79 | TNF (0.33) | — | |
| SCHEMBL11210746 | 0.76 | MAPT (0.33) | — | |
| SCHEMBL10744133 | 0.76 | ACP1 (0.35) | — | |
| SCHEMBL11235805 | 0.75 | TAAR1 (0.36) | SMN1; SMN2 | |
| SCHEMBL12738142 | 0.73 | — | — | |
| SCHEMBL11210877 | 0.73 | PTGER1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034474-B1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Farmos-Yhtyma Oy (FI) | 1983-01-26 | — | — | EP | disclosed |
| US-4333947-A | HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES | FARMOS-YHTYMA OY (FI) | 1982-06-08 | — | — | US | disclosed |
| EP-0034474-A1 | Substituted imidazoles, their preparation and pharmaceutical compositions containing the same | Farmos-Yhtyma Oy (FI) | 1981-08-26 | — | — | EP | disclosed |