SCHEMBL11209273

SCHEMBL11209273

Cc1ccc(CC=Cc2c[nH]cn2)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.33
PYCR1 P32322 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11235805 0.82 TAAR1 (0.36)
SCHEMBL11210746 0.81 MAPT (0.33)
SCHEMBL11205166 0.79 AGXT (0.32)
SCHEMBL11266744 0.78 IDO1 (0.39)
SCHEMBL11210877 0.77 PTGER1 (0.33)
SCHEMBL10744133 0.75 ACP1 (0.35)
SCHEMBL11206958 0.74 TYR (0.40)
SCHEMBL11045882 0.71 TNF (0.36) TNFPYCR1
SCHEMBL11208188 0.71 TAAR1 (0.36)
SCHEMBL11208108 0.71 HSPA5 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4333947-A HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES FARMOS-YHTYMA OY (FI) 1982-06-08 US claimed
EP-0034474-B1 SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Farmos-Yhtyma Oy (FI) 1983-01-26 EP disclosed
US-4333947-A HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES FARMOS-YHTYMA OY (FI) 1982-06-08 US disclosed
EP-0034474-A1 Substituted imidazoles, their preparation and pharmaceutical compositions containing the same Farmos-Yhtyma Oy (FI) 1981-08-26 EP disclosed