Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.57 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5256567 | 1.00 | GABRA1 (0.57) | GABRA1GABRB2HSPA5MGLLTP53 | |
| SCHEMBL25425763 | 0.90 | GABRA1 (0.58) | GABRA1GABRB2MGLLTP53MAPT | |
| SCHEMBL36294 | 0.90 | GABRA1 (0.58) | GABRA1GABRB2MGLLTP53MAPT | |
| SCHEMBL29390847 | 0.90 | GABRA1 (0.58) | GABRA1GABRB2MGLLTP53MAPT | |
| SCHEMBL11205678 | 0.87 | HTR2A (0.54) | GABRA1GABRB2TP53L3MBTL1LMNA | |
| SCHEMBL11210876 | 0.87 | TAAR1 (0.46) | GABRA1GABRB2KMT2AALDH1A1 | |
| SCHEMBL6548002 | 0.87 | TAAR1 (0.46) | GABRA1GABRB2KMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL2638008 | 0.87 | GABRA1 (0.55) | GABRA1GABRB2MGLLTP53MAPT | |
| SCHEMBL14807864 | 0.87 | GABRA1 (0.55) | GABRA1GABRB2MGLLTP53MAPT | |
| Benzene SCHEMBL3122858 | 0.87 | TP53 (0.56) | GABRA1GABRB2MGLLTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |