Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 10/20 | 0.57 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205539 | 1.00 | AGTR2 (0.57) | AGTR2BDKRB2ACE | |
| SCHEMBL11205530 | 1.00 | AGTR2 (0.57) | AGTR2BDKRB2ACE | |
| Hydrochloric Acid SCHEMBL11199338 | 0.99 | AGTR2 (0.56) | AGTR2BDKRB2ACE | |
| Hydrochloric Acid SCHEMBL11199335 | 0.99 | AGTR2 (0.56) | AGTR2BDKRB2ACE | |
| Hydrochloric Acid SCHEMBL7313973 | 0.99 | AGTR2 (0.56) | AGTR2BDKRB2ACE | |
| Hydrochloric Acid SCHEMBL11202611 | 0.99 | AGTR2 (0.56) | AGTR2BDKRB2ACE | |
| Hydrochloric Acid SCHEMBL11202613 | 0.99 | AGTR2 (0.56) | AGTR2BDKRB2ACE | |
| SCHEMBL7338505 | 0.86 | ACE (0.58) | AGTR2ACE | |
| SCHEMBL7349421 | 0.86 | ACE (0.58) | AGTR2ACE | |
| SCHEMBL7338501 | 0.86 | ACE (0.58) | AGTR2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080822-A1 | Anti-hypertensive prolinol-based peptides | BEECHAM GROUP PLC (GB) | 1983-06-08 | — | — | EP | disclosed |