Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 7/20 | 0.47 |
| ▸ | KIT | P10721 | 4/20 | 0.47 |
| ▸ | FLT3 | P36888 | 4/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 6/20 | 0.45 |
| ▸ | PRKACA | P17612 | 5/20 | 0.45 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 4/20 | 0.45 |
| ▸ | LCK | P06239 | 3/20 | 0.45 |
| ▸ | CSF1R | P07333 | 3/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.45 |
| ▸ | PLK4 | O00444 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13264637 | 0.86 | GAA (0.56) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL11203656 | 0.81 | GAA (0.44) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL16681490 | 0.75 | MAP2K1 (0.59) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL5181390 | 0.75 | PDPK1 (0.51) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL6854925 | 0.75 | GAA (0.51) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL12322134 | 0.75 | CSNK1A1 (0.36) | KDRFLT3PDGFRBCSNK1A1KDM4E | |
| SCHEMBL12281543 | 0.75 | ELANE (0.39) | CSNK1A1KDM4ECSNK1D | |
| SCHEMBL11206157 | 0.75 | HTR2A (0.49) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL5171279 | 0.73 | PDPK1 (0.49) | PDPK1GAAMAP2K1KDRKIT | |
| SCHEMBL569660 | 0.73 | GAA (0.61) | PDPK1GAAMAP2K1KDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090972-A2 | Indazole derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-10-12 | — | — | EP | disclosed |
| EP-0049779-A1 | 3-Aminoindazole derivatives and process for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-04-21 | — | — | EP | disclosed |