Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273169 | 0.79 | SLC6A2 (0.50) | HTR2ASLC6A2HTR1AHTR2CHTR6 | |
| SCHEMBL11205992 | 0.75 | PDPK1 (0.53) | GAAPDPK1MAP2K1KDRKIT | |
| SCHEMBL11203656 | 0.73 | GAA (0.44) | HTR2ASLC6A2HTR1AGAAPDPK1 | |
| SCHEMBL11279156 | 0.73 | ROCK1 (0.37) | HTR2ASLC6A2GAAPDPK1MAP2K1 | |
| SCHEMBL28900212 | 0.72 | SIGMAR1 (0.51) | HTR2ASLC6A2SIGMAR1DRD2SLC6A4 | |
| SCHEMBL18926549 | 0.72 | LTA4H (0.59) | HTR1ASIGMAR1DRD2SLC6A4SLC6A3 | |
| SCHEMBL13264637 | 0.71 | GAA (0.56) | GAAPDPK1MAP2K1KDRKIT | |
| SCHEMBL18405305 | 0.70 | SIGMAR1 (0.49) | HTR2ASLC6A2SIGMAR1DRD2SLC6A4 | |
| SCHEMBL10315568 | 0.69 | SLC6A3 (0.50) | HTR2ASLC6A2SIGMAR1MPODRD2 | |
| SCHEMBL23123879 | 0.69 | HTR1A (0.46) | HTR2ASLC6A2HTR1AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090972-A2 | Indazole derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-10-12 | — | — | EP | disclosed |